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2009ǯ11·î18Æü(¿å)

??????????????????????????FDA?

Åê¹Æ¼Ô: ????????

?PPI??????????????????????????????????????????TOPICS 2009.01.29????????????17??FDA???????????????????????????PPI?????????????????????????????

Updated Safety Information about a drug interaction between Clopidogrel Bisulfate (marketed as Plavix) and Omeprazole (marketed as Prilosec and Prilosec OTC)
?FDA 2009.11.17 Public Health Advisory ?
http://www.fda.gov/Drugs/DrugSafety/PublicHealthAdvisories/ucm190825.htm

??????????????????Vol.7 No.25??????????
http://www.nihs.go.jp/dig/sireport/weekly7/25091210.pdf

Update to the labeling of Clopidogrel Bisulfate (marketed as Plavix) to alert healthcare professionals about a drug interaction with omeprazole (marketed as Prilosec and Prilosec OTC)
?FDA 2009.11.17 Information for Healthcare Professionals?

Follow-Up to the January 26, 2009, Early Communication about an Ongoing Safety Review of Clopidogrel Bisulfate (marketed as Plavix) and Omeprazole (marketed as Prilosec and Prilosec OTC)
FDA 2009.11.17?

?FDA???Sanofi-Aventis ?? Bristol-Myers Squibb ???????????????????????????????????????CYP2C19????????????????????????????????

????????????????????????????45?????????47????????????????????????12??????????????????????

????????FDA?????????????????

  • ????????????????????????????????????
  • ????????????????????????????????????????????OTC???????????????????
  • ?????????????????????????????????????????????????????????
  • ?????????????????????????????OTC?????????????????????????

????????????????????????????????

  • esomeprazole????????????????????
  • ???????PPI????????????????????????????
  • ??????????????????????voriconazole?etravirine?felbamate??????????????????????????CYP2C19??????????????????????????????????????

PLAVIX?FDA Label Information 2009.11.12?
http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020839s044lbl.pdf

?Healt? Day ??????????????????????????????????????????????????????????

?????TOPICS?2009.01.29?PPI??????????????????????

???Heartburn Drugs Can Thwart Popular Blood Thinner
????Health Day?2009.11.17?
????http://www.healthday.com/Article.asp?AID=633204

12?10??????

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¥³¥á¥ó¥È (2)

  1. ?????????????????????????

    ????????????????????LANCET????????????????????????????????????????????????????
    http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)61525-7/abstract

    ??????????????????????????????????

    ????????
    http://chuopharm.dtiblog.com/

    Åê¹Æ¼Ô by ???????? — 2009ǯ11·î18Æü(¿å)15:54

  2. ???????????????

    ?????????????????????????????????????

    ?????????????????????Label Information ??????????????????????????????????????????

    ???????????????????????????????????????LANCET???????????????

    ??AP??????????????? Public Citizen ????????????????“black box”warning label????????????????

    ?????????????????????????????????

    FDA says heartburn drugs can interfere with Plavix
    ??CNBC 2009.11.17 AP???
    ?http://www.cnbc.com/id/33991224

    Åê¹Æ¼Ô by ???????? — 2009ǯ11·î18Æü(¿å)17:20

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