?????R?????????

?2010.02.19 ?TOPICS???FDA??LABAs?????????????????????????????????????????????2??NEJM ??Online First ???????????????????????????????????????????????????????????????????LABAs??????????????????????????

Step-up Therapy for Children with Uncontrolled Asthma while Receiving Inhaled Corticosteroids
??New Engl J Med 2010.3.2 Online First?
?http://content.nejm.org/cgi/content/full/NEJMoa1001278

Choosing Asthma Step-up Care
??New Engl J Med 2010.3.2 Online First?
?http://content.nejm.org/cgi/content/full/NEJMe1002058

?????????????100mg?1?2???????6?17?????182???Step-up?Care?????????????250mg?1?2?????LABAs????????50mg?1?2??????????????????????????5mg???10mg????3??????16??????????????????????LABAs?????????????????????????????????????????????????????????????????

??????????AAAAI:American Academy of Allergy, Asthma & Immunology??????????????????????????FDA?LABAs????????????????????????????????LABAs????????????????????????????

????????????????????????????????????????????????????????Step-up????????????????????????????????

????????????????????????????????????7???????????????????Step-up?????????????????????????????????????????????????????????

????LABAs???????????????????????????

Long-acting Beta-Agonists with and without Inhaled Corticosteroids and Catastrophic Asthma Events
?The American Journal of Medicine published online 22 February 2010.?
http://www.amjmed.com/article/S0002-9343(09)01110-3/abstract

???????????ICS????????????
?????????????2010?2?22??
http://intmed.exblog.jp/10022670

??????????????????????FDA???????????????????????????????

????:TOPICS
?2010.02.19?????LABAs???????????????(?FDA)
?2008.12.12?FDA????LABA????????????????
?2009.07.09???????????????????????
?2009.06.13????????????????????????FDA?

???
AAAAI:Asthma ‘Step-Up’ Tx Works Most Often with LABAs
?Medpage TODAY 2010.3.2?
http://www.medpagetoday.com/MeetingCoverage/AAAAI/18772
Panel Critical of FDA’s Asthma Drug Ruling
?WebMD?2010.3.1?
http://www.webmd.com/asthma/news/20100301/panel-critical-of-fda-asthma-ruling