???????????????????MHRA?
?MHRA??????????3?�Drug Safety Update�?�Public Assessment Report�?????5?-?????????????????????Update????????
Finasteride and the risk of male breast cancer
??Safety warnings, alerts and recalls 2009.12.3?
The risk of male breast cancer with finasteride
? (MHRA PUBLIC ASSESSMENT REPORT 2009.12 PDF 329KB)
Drug Safety Update: Volume 3, Issue 5, December 2009
http://www.mhra.gov.uk/Publications/Safetyguidance/DrugSafetyUpdate/CON065444
???????????????????5mg??Proscar???????????????1mg????????????????????HRA?????????????????????????????????Public Assessment Report ???????????
?????????????????????????2009?11????5mg??50??1mg??3??????????????????5?????????????????????????????????????????????10?????7.8??3.8??
???????MHRA????????APCs?Summaries of Product Characteristics??�Special warnings and precautions for use�???????????????????????????????????????????????????????????????????????????????????(?)??????????????????????????????????????????PIL?patient information leaflets???????�Possible side effects�??????????????????????????????????????????????????????????????????
?????????????????????????????????????????????????????????????????????????????????????????
?????Finasteride - risk of male breast cancer
?Pharmacovigilance Working Party monthly reports OCTOBER 2009?
?http://www.emea.europa.eu/pdfs/human/phvwp/66624309en.pdf
??????????????Vol.7 No.25???
?http://www.nihs.go.jp/dig/sireport/weekly7/25091210.pdf
12?10???