???????????????????????????
???????????????????????????????????Heart ??Online?First??????????
Alcohol intake and the Risk of coronary heart disease in the Spanish EPIC cohort study
?Published Online First: 19 November 2009.10.1136/hrt.2009.173419.?
http://heart.bmj.com/cgi/content/abstract/hrt.2009.173419v1
???????29??69???????????15,630????25,808????????? cohort study??????????????10??????????????????CHD?coronary heart disease??????????????????????????????????????(???????????????????????p values ???)
| ?? | ????? ??? |
?? | ?? | ?? |
|---|---|---|---|---|
| former | HR 0.86 (95% CI 0.54-1.38) |
HR 1.17 (95% CI 0.66-2.08) |
||
| low | 0?5 mg/day | HR 0.65 (95% CI 0.41-1.04) |
HR 0.64 (95% CI 0.4-1.0) |
HR 0.75 (95% CI 0.48-1.17) |
| Moderate | 5?30mg/day | HR 0.49 (95% CI 0.32-0.75) |
HR 0.47 (95% CI 0.31-0.73) |
HR 0.62 (95% CI 0.36-1.07) |
| high | 30?90mg/day | HR 0.46 (95% CI 0.30-0.71) |
HR 0.45 (95% CI 0.29-0.69) |
HR 0.21 (95% CI 0.03-1.52) |
| very high | 90mg/day? | HR 0.50 (95% CI 0.29-0.85) |
HR 0.49 (95% CI 0.28-0.86) |
????????????????????????????????(CHD????????1/3?1/2)??????????????????
????????????????????????????????????HDL-C????????????????????????????
??????????????????????????????????????????
???
Alcohol Cuts CHD Risk in Men?MedPage TODAY 2009.11.18?
?http://www.medpagetoday.com/Cardiology/Prevention/17095
Moderate Drinking Guards the Heart?Health Day 2009.11.19?
?http://www.healthday.com/printer.asp?AID=633260