???????????????????????
??FDA?8?????????????????????????????????????????????
?Information for Healthcare Professionals Simvastatin (marketed as Zocor and generics), Ezetimibe/Simvastatin (marketed as Vytorin), Niacin extended-release /Simvastatin (marketed as Simcor), used with Amiodarone (Cordarone, Pacerone)
??http://www.fda.gov/cder/drug/InfoSheets/HCP/simvastatin_amiodaroneHCP.htm
?Information on Simvastatin/Amiodarone(FDA2008.8.8?
??http://www.fda.gov/cder/drug/infopage/simvastatin_amiodarone/default.htm
?Simvastatin Used With Amiodarone?FDA Medwatch?2008.8.8.?
??http://www.fda.gov/medwatch/safety/2008/safety08.htm#Simvastatin
?????????????? ???????? Vol.6 No.19 ?????????
????http://www.nihs.go.jp/dig/sireport/weekly6/19080918.pdf
?FDA????????????CYP3A4????????????????????????????????1??????20???????????????????????????
?AP???????FDA????????????????????????52?????????????FDA?????????????????????????20??????????????????
?????????????????????????????????????????????????????????????????????????????
9?23???????