PPI???????????????????????(????)
???????????????????????????????????????????????????????hip fracture??????44??????????????????????????????2.6???????????????????JAMA??????????????Long-term Proton Pump Inhibitor Therapy and Risk of Hip Fracture
??JAMA. 2006;296:2947-2953?
??http://jama.ama-assn.org/cgi/content/abstract/296/24/2947
??http://jama.ama-assn.org/cgi/content/full/296/24/2947
?????????50????15???????77?????79?????????????????????nested case-control study?????????????????????????????
?????????????????????????????????????????????????22????????59??????????????????????????????????
?????????????????????????????????????????????????????????????????????????????????????????????????PPI???????????????????????????????????????????????
???PPIs associated with increased risk of hip fractures
?????pharmacist.com.news 2006.12.27?
?????http://www.pharmacist.com/articles/h_ts_1353.cfm
????Acid Reflux Drugs May Up Fractures?WebMD 2006.12.26?
?????http://www.webmd.com/content/article/131/117904.htm
????????12?27?